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Cerium Oxide

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Cerium Oxide || Research || Sources

Cerium Oxide

Cerium Electron Arrangement

Cerium is the single most abundant rare earth mineral (metal) and is well known for its high reactivity. It is often found in trace amounts in water and soil and has numerous industrial uses in refined form.

In recent years, researchers have begun studying refined cerium oxide nanoparticles for medical applications. A study of the available medical literature has slowly been revealing that cerium may be a vital trace mineral with profound health implications.



Key Research

Cerium Oxide has been tested and used in medicine to treat diseases associated with free radical damage and inflammation, including neurology disease conditions such as Alzheimer’s. Cerium Oxide (CeO) has a higher absorption of ultraviolet radiation than zinc oxide and titanium oxide.

Numerous patents have been filed claiming that cerium oxide nanoparticles are beneficial in treating the following conditions:

brain diseases

spinal cord diseases

neurological trauma

neurodegenerative disorder

Alzheimer’s disease

Parkinson’s disease

Huntington’s disease

amyotrophic lateral sclerosis (ALS)

multiple sclerosis

toxin-mediated damage



arthritis or joint disease

cardiovascular disease


diseases of the retina

allergic or autoimmune disorders



chronic obstructive pulmonary disease

respiratory dysfunction

autoimmune disease

micro and macro inflammation

inflammation in wounds

UV and radioactive induced inflammation and cell trauma



For example, a study conducted by David Schubert et al (1) determined that cerium and yttrium nanoparticles act as direct antioxidants which limit the amount of reactive oxygen species required to kill the cells. The researchers concluded that this group of nanoparticles could be successfully used to modulate oxidative stress in biological systems.

A further study demonstrated that cerium was cardioprotective. An in-vivo experiment involving mice via intravenous injection of CeO2 conclusively demonstrated the beneficial effects of cerium. The research, conducted by Jianli Niu et al (2), concluded that the cerium protected the mice against the progression of cardiac dysfunction and remodeling.

The method of action? The attenuation of myocardial oxidative stress, ER stress, and inflammatory processes. The researchers speculated that the cerium had significant autoregenerative antioxidant properties.

Another study concluded that rare earth cerium, due to its free radical scavenging properties, protects normal tissue from damage caused by radiation. Specifically, the cerium prevented the onset of radiation-induced pneumonitis in animals exposed to high doses of radiation. The researchers noted that the cerium is well tolerated by living animals. (3)

Furthermore, a group of researchers concluded that ultrafine cerium oxide nanoparticles contributed to cell survivability. Cultured cells subjected to cerium nanoparticles lived longer. The researchers hypothesized that the cerium oxide would be beneficial in wound care management, and the treatment of arthritis and inflammatory joint conditions.(4)


1. David Schubert, Richard Dargusch, Joan Raitano, and Siu-Wai Chan of The Salk Institute and Columbia University, Departments of Applied Physics and Applied Mathematics, January 3, 2006, published in Biochemical and Biophysical Research Communications 342 (2006) 86–91

2. Jianli Niu, Asim Azfer, Linda M. Rogers, Xihai Wang, and Pappachan E. Kolattukudy, Biomolecular Science Center, Burnett College of Biomedical Science, University of Central Florida, Orlando, FL 32816, US

3. Protection from radiation-induced pneumonitis using cerium oxide nanoparticles, Jimmie Colon, MS, Luis Herrera, MD, Joshua Smith, BS, Swanand Patil, PhDd, Chris Komanski, BS, Patrick Kupelian, MD, Sudipta Seal, PhD, D. Wayne Jenkins, MD, Cheryl H. Baker, PhD, Nanomedicine, Volume 5, Issue 2, Pages 225-231 (June 2009

4. United States Patent 7534453

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Nutritional Sources for Cerium

Sea Vegetables

Much of the available information regarding the use of cerium for health relates to unnatural and highly processed cerium oxide nanoparticles used for medical research. However, by choosing the right food sources and natural supplements, one can safely consume trace amounts of cerium as a part of a healthy diet and lifestyle.

Please note that trace minerals should only be consumed in very minute amounts, in forms that exist in natural food ecosystems, and not in any concentrated form. Consuming any trace mineral in a concentrated form may have unintended and potentially catastrophic effects.


Sea Vegetables


Sea Vegetables - Not affected by soil depletion, sea vegetables provide a natural and balanced source of cerium.

Ionic Mineral Supplements - The quality of ionic mineral supplements vary greatly, and it is difficult to gauge whether or not one is actually overdosing on trace minerals, since very few ionic mineral supplements are actually natural, even the ones that claim to be plant based.

Sea Salt and Sea Mineral Supplements (inorganic) - Most sea mineral products, including sea salts, have trace amounts of cerium.

Greens / Vegetables - A natural source for bioavailable trace minerals, however, due to poor soil conditions caused by modern farming practices, soils are often depleted of valueable nutrients.

Therapeutic edible green clays - Completely natural dietary source for cerium oxide. According to research conducted for NASA on edible calcium bentonite, therapeutic clays not only provide trace minerals that act at the cellular level in the body, but they can correct maladsorption issues.(5)


5. Eaton, Jason R. (2009) Upon a Clay Tablet, Volume I " Las Vegas, NV: AV Websites Marketing Group, pp 191-193, Dr. Benjamin Ershoff, Ph.D., pp 301-331

Links to Outside Resources

Cerium study published by Science Direct done by Schubert et al (cited above).

Cardioprotective Effects of Cerium - Journal abstract.

Cerium, Periodic Table - Cerium minerology information at

Liqumins ConcenTrace Trace Mineral Drops - This is one source we use as a trace mineral water additive (, although we only use about one drop of water per gallon.

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