The Story of Ozone
9: Methods of Application



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Since ozone therapy was first practiced in the 1880s, many methods of administering ozone have been developed. They can be broken down into five categories :

1) Injection - autohemotherapy; or direct injection into a vein, artery, muscle, joint; or directly into a tumor

2) Insufflation - in the ear, vagina, rectum, urethra

3) Inhalation - bubbled through olive oil

4) Ingestion - ozonated water

5) Transdermal - subatmospheric; bagging; body suit; ozonated olive oil; cupping with a funnel; steam sauna

Direct Injection vs. Autohemotherapy

Autohemotherapy was developed by Dr. Hans Wolff in 1961 as an alternative to direct injection. Dr. Wolff developed a technique for withdrawing 50 - 500 cc of blood into a container, injecting ozone into it and then infusing it back into the patient over 20 minutesas an IV drip.

There were several problems to be overcome. Blood coagulates when it is exposed to the air, so a method had to be found to prevent coagulation. The liver normally secretes heparin to prevent clotting inside the body. Sodium heparin was found to be effective in preventing clotting outside the body. Later, when heparin was seen to cause problems in some patients with liver problems (especially cirrhosis), sodium citrate was adopted by some doctors. However, heparin is still widely used because sodium citrate is less effective, even though heparin is hard on the liver and is known to suppress the immune system.

A suitable vessel to hold the blood was required, and the Hansler corporation of Germany began to manufacture and market a vacuum flask kit to make it easier for doctors to perform this therapy. Hansler GmbH is the oldest medical ozone generator company still in business, based upon Dr. Joachim Hansler's 1957 patent of a dual-dielectric corona
discharge ozone generator tube.

There are a number of advantages of direct injection vs. autohemotherapy :

  • there is no need for heparin, which can damage the liver and is immune-suppressive, and may cause uncontrolled bleeding
  • there is no need for an expensive, disposable vacuum flask kit and no contaminated equipment to dispose of afterward
  • there is no need to take time to mix the ozone into the blood, or wait for the reinfusion drip
  • since the heart will pump all the blood past the point of injection in eight minutes, all 6 liters of the blood are cleaned, instead of just 50 - 500 cc
  • it is easier to initiate the desirable healing crisis
  • fewer treatments are required because a better job is done each time
  • a tumor can be injected directly and then the resulting fluid aspirated with the same needle


Insufflation is very useful, easily done, inexpensive, and now widely used in the home.

Insufflation in the ear is excellent for: ear infections; mastoiditis; hearing problems caused by candida; tinnitus; (and beyond the ear to) sinusitis; macular degeneration; retinitis pigmentosa; head colds; flu; bronchitis; asthma; Alzheimer's; Parkinson's; even brain cancer.

  • Vaginal insufflation is used for any vaginal, uterine, ovarian or lower abdominal problem, including pelvic inflammatory diseases, fibroids, etc. The ozone will enter the lymph system from vaginal insufflation, as well as the blood stream.
  • Rectal insufflation requires a preparatory enema. It is used for colon problems such as colitis, ileitis, irritable bowel, Crohn's disease, and colon cancer.
  • Urethral insufflation is used for bladder infections, STDs, inflammation of the ureter, prostate enlargement, and bladder and prostate cancer.


Ozone can be inhaled if it is first bubbled through extra virgin olive oil. This is useful for asthma due to bacterial or viral infection. Repeated treatments over 3 - 6 weeks for 15 - 20 minutes at a time are usually sufficient. Simultaneous magnet therapy is useful and can be easily done by placing a magnet (3" x 5"; 3500 gauss) on the chest with the north pole
facing the body.


Six to eight glasses a day will establish a high level of oxygenation in the body and assist detoxification. Bubble ozone into a glass of water for 5 - 10 minutes, then drink on an empty stomach. This will also destroy helicobacter pylori in the stomach, which is the cause of ulcers.


Transdermal application of ozone has existed for 120 years, and recently has been growing in popularity. The skin is semi-porous to oxygen, and 7% of normal respiration is transdermal. There are several transdermal ozone application techniques:

A) Subatmospheric B) Bagging a limb C) Body suit D) Ozonated olive oil E) Cupping with a funnel F) Steam cabinet

A) Subatmospheric application requires an apparatus to enclose a limb, reduce pressure by means of a vacuum pump and direct ozone into proximity with the desired area. This technique has proven useful in certain difficult problems, such as gas gangrene and open ulcers. It is not widely used at present because of the expense of the equipment and its lack of availability.

B) Bagging a limb is very similar, but requires only a clear plastic bag in order to confine the ozone to the area being treated. The limb is moistened first, in order to aid the penetration of ozone through the skin, then enclosed in the plastic bag and the ozone is introduced by means of silicone tubing from the generator into the bag. The top of the bag
is securely closed with either a cloth strip or an elastic strap as a cuff. If the flow rate is to be above 1/8 l/m, then an outlet from the bottom of the bag will be necessary to allow the excess ozone to leave, and avoid pressurization. If the flow rate is kept very low, say 1/16 l/m or 1/32 l/m, there is no need to have an outlet, as the bag will not overfill in a 30 minute treatment. This technique has been in use for many years, and is especially useful with impaired circulation in diabetic legs, removing the threat of amputation.

C) A body suit is composed of ozone-resistant material, typically Tyvek or nylon, which is sealed at the wrists, neck and ankles (if there are no attached booties). It is necessary to shower first and then enter the suit while still wet, to aid ozone transference. The silicon tubing from the generator is introduced into the suit either through the neck opening or up the sleeve. Ozone is introduced for 30 minutes at a rate of 1/8 l/m or 1/4 l/m. This method is losing favor due to the clammy, sticky feel of the suits on the skin, as the wet skin surface cools and dries.

D) Ozonated olive oil has been used as a topical application for 100 years and its efficacy is well established for problems such as acne, cuts, scrapes, bruises, burns, eczema, sunburn, skin infections, etc. It is also useful to apply it to the skin following a session of limb bagging.

E) Cupping with a funnel is a more recent transdermal technique where ozone is introduced into a very restricted area at a very low flow rate. First the area to be treated (typically the liver, pancreas, spleen, intestine, kidney or adrenal) is moistened with a warm washcloth, and then a plastic funnel is held firmly over the area. The flow rate is restricted to 1/32 l/m
in order to prevent pressure buildup under the cup, and possible leakage. Treatments typically run for 20 - 30 minutes. Good results are obtainable with daily application for hepatitis, diverticulitis, pancreatitis, kidney infections and adrenal insufficiency.

F) The sixth transdermal technique was developed by Dr. John Kellogg in 1880, and revived by the introduction of the units that we distribute in 1994, to take advantage of the therapeutic possibilities of using hyperthermia in conjunction with ozone therapy. The person sits in an ozone-resistant steam cabinet, with the head out, and the body surrounded by warm steam. The steam causes the pores to open fully and the ozone, introduced into the cabinet by silicon tubing from the generator output, can penetrate fully into all the tissue - the blood, the lymph and the fat. Since the majority of toxins are held in the lymph and the fat, this treatment is the most effective way to eliminate them from the body. The skin is the largest organ of elimination, and the majority of the oxidized toxins are sweated out, sparing the liver and kidneys most of the extra work.

Hyperthermia itself is a very effective technique, many thousands of years old, recommended by Hippocrates. It results in a "false fever" reaction, which simulates the body's own defense mechanism. With the addition of ozone, the treatment becomes doubly powerful. As the toxins are oxidized, and eliminated from the body, the fat containing them
is no longer needed, and also leaves. Weight loss of 30, 40, or 50 lbs over a period of months has been reported, with no change in diet. The skin becomes smooth, soft and free of blemishes. Symptoms of a whole host of diseases disappear as the toxins leave the system and the body is enabled to heal itself.

Unlike other methods of ozone application, employing ozone in a steam sauna will induce the "healing crisis", which feels like having the flu for a few days. People should be informed of this effect so they can be prepared, and welcome it as a sign of beneficial healing. Skin rashes are common as the toxins are pushed out through the skin rapidly. Often the rash is very itchy, and this can be alleviated by taking protease enzymes, and applying Gardener's Dream Cream.

The more frequent the treatments, the more rapid the healing, and the more severe the healing reactions will be. It may become so uncomfortable that the person will need to reduce the frequency of treatments from once daily to once weekly. Typical treatments are once daily for 30 minutes duration. Persons with heart conditions should be limited to 15 minutes at a lower temperature for the first few sessions, increasing to 20, 25 and then 30 minutes, as the body adjusts to the thermal stress over time. People who have had a previous stroke should not do saunas, but can do ozone in other ways.

Flow rate of ozone into the cabinet is at 1/2 l/m in order to fill the large volume and overcome the loss of ozone to heat. Concentration ranges from 35 to 40 ug/ml. A series of treatments usually consists of 10-30 applications.

The effect of the ozone on any particular organ can be intensified by cupping with a funnel while in the steam cabinet. This is especially effective with hepatitis, diverticulitis, pancreatitis and cancer. It also involves the person in actively taking responsibility for initiating the healing process. Flow rate for cupping should be at 1/8 l/m, with concentrations from 40 - 50 ug/ml.

Novel application techniques are: placing the output tubing in the armpit and holding the arm against the body, so that the ozone enters the lymph system; placing the end of the tubing in the mouth to treat the teeth, (carefully avoiding inhaling, or swallowing); and sitting on the end of the tubing, so that ozone enters the perineum area.

Transdermal application of ozone combined with hyperthermia in the steam cabinet is the treatment of choice for all cancers (brain cancer treatment can be supplemented with ozone insufflation in the ear at 1/32 l/m). Cancer tumor cells are tightly packed as they try to force their way in between other cells, and they are thus less able to shed heat. This accounts for effect that heat stress has in killing cancer. Both heat stress and ozone kill cancer, so this treatment offers the best opportunity to eliminate cells which are fermenting sugar anerobically, halt metastasis and restore healthy aerobic function. Ozone is able to seek out and destroy all the cancer cells with more certainty than the surgeon's crude scalpel. In addition, ozone will oxidize the toxins which caused the original problem, and thus prevent recurrence. This is in stark contrast to chemotherapy, which is massively immune-suppressive, and radiation which actually causes cancer.

Using ozone with hyperthermia in the steam sauna will cleanse all the tissues of the body and provoke the healing crisis, which is not seen with other delivery methods, proof that this is the best way to achieve thorough cleansing of all toxins.

It is critical that the bowels remain open during these treatments, in order that oxidized toxins are completely eliminated from the system and not reabsorbed. The best methods of insuring this is by ingestion of 6 - 8 glasses of ozonated water daily (always on an empty stomach), large amounts of fiber (such as psyllium or pectin), large amounts of natural Vitamin C (3000 mg three times daily), flax oil and/or Homozon.

In combination with a comprehensive diet plan, parasite, liver and colon cleanses, and suitable exercise, this program offers the best chance for a person to recover optimum health.

Goto the Next Chapter: Hyperthermia


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Ozone Therapy & Generators

The Story of Ozone


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